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Migraines may be doing more than causing debilitating headaches. According to a new study, people with migraines could experience faster brain ageing, with researchers identifying changes that may have lasting consequences for brain health.
Previous studies show evidence that migraines may be linked to long-term changes in brain health, including an elevated risk of cognitive decline and dementia. The new study focused on brain age gaps, a measure that compares a person's chronological age with the apparent age of their brain. Larger gaps are often associated with accelerated brain ageing and a greater likelihood of future cognitive decline.
Using MRI scans from 110 people with migraines and 70 non-migraine participants, researchers assessed over 400 brain regions and calculated estimated brain age with the help of a computer algorithm. They discovered 66 regions that appeared biologically older than expected, with the most pronounced changes occurring in areas involved in pain processing, emotional responses, and cognition.
The findings showed that migraine patients had a brain age gap that was, on average, 4.24 years greater than that of participants without migraines. The largest differences were observed among individuals with chronic migraines.
These results underscore the importance of gaining a deeper understanding of the long-term effects migraines may have on the brain. Further research is needed to clarify how migraines may contribute to cognitive decline and other age-related neurological changes.
To view the original scientific study click below:
Accelerated brain ageing in migraine: a multilevel MRI-based brain-age modelling study
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