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Recent research reveals that constipation is linked to a greater risk of heart attacks and strokes, with the danger escalating significantly in individuals who also suffer from high blood pressure. These findings underscore the importance of viewing constipation not merely as a digestive problem, but as a potential cardiovascular risk factor requiring serious attention.
If you suffer from chronic constipation, it's crucial to understand its potential consequences and seek effective remedies, as improving gut health is gaining recognition as a promising approach to preventing heart disease.
Researchers drew on health records from over 400,000 UK Biobank participants to examine whether constipation qualifies as a novel, independent risk factor for heart disease. Their analysis found that people reporting constipation were at markedly greater risk of major adverse cardiovascular events (MACE) than those with normal bowel habits.
Among the participants, over 157,400 had hypertension, and 8.6% of this group also suffered from constipation. Individuals with constipation showed a markedly elevated risk of major adverse cardiovascular events. Overall, 11.5% of those studied had experienced at least one such event, with substantially higher rates observed in men.
The elevated risk of MACE persisted even after adjusting for medications known to cause constipation, such as calcium channel blockers commonly prescribed for blood pressure management. Additionally, the researchers discovered a notable genetic overlap, with up to 27% of the genetic variants associated with constipation also linked to cardiovascular conditions.
These latest findings highlight the connections between constipation and cardiovascular disease, paving the way for scientists to develop novel treatments and adopt more targeted management approaches tailored to individual risk profiles.
To view the original scientific study click below:
Constipation is associated with an increased risk of major adverse cardiac events in a UK population
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