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Beyond heart benefits, intense exercise packs an even greater benefit. A recent study shows that just 10–12 minutes of high-intensity activity can slow the growth of colorectal cancer cells. Scientists explored the effects of exercise on colorectal cancer cells. While previous studies have demonstrated that exercise offers protective benefits against cancer, this research sought to deepen our understanding of the underlying molecular processes.
The likelihood of developing colorectal cancer increases as people get older, with added risks from genetic factors and habits like consuming high amounts of red meat. This remains one of the most common cancers in the United States, expected to affect over 150,000 people a year.
Early detection of colorectal cancer allows for simpler treatment, often just surgery to remove the tumor, while advanced cases typically involve surgery plus chemotherapy or radiation. Since prior studies have suggested exercise can be helpful for individuals with colorectal cancer, the researchers in this latest investigation aimed to better understand how these benefits take place at a biological level.
The study involved 30 healthy but overweight or obese adults between the ages of 50 to 78. Participants performed an intense cycling session lasting about 10 minutes, after which researchers analyzed their blood, which resulted in detection of changes in the activity of more than 1,300 genes. Genes involved in cellular energy production ramped up, while those associated with aggressive cancer cell growth were suppressed. They also identified a specific blood molecule that activates DNA repair pathways, indicating that even brief intense exercise can meaningfully impact key cellular mechanisms.
The findings suggest real potential, but they are far from definitive and call for further rigorous investigation. Future work should focus on prospective clinical trials to clarify whether short bursts of intense exercise can genuinely improve survival rates, recurrence risk, or other key measures for colon cancer patients.
To view the original scientific study click below:
Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells
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