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A well-balanced gut microbiome is essential for supporting overall health, including the absorption of essential bone-building nutrients. When gut health declines, the body's ability to absorb these nutrients is compromised. Studies have connected a healthy gut microbiome to improved bone density.
The gut-bone axis describes the intricate relationship and communication between the gut microbiome and the skeletal system. Previous research on skeletal health and disorders has increasingly focused on the gut-bone axis. A key pathway extensively studied is inflammation, particularly how an unhealthy microbiome can contribute to bone loss.
Specific gut bacteria improve nutrient solubility and absorption in the intestines. Some produce proteins that bind to calcium, facilitating its transport and utilization, especially in the bones.
Dysbiosis, an imbalance in gut bacteria, can damage the gut lining, allowing harmful substances to leak into the bloodstream. This sparks widespread inflammation, accelerating bone degradation and disrupting the balance between bone resorption and formation. Subsequently, this can contribute to disorders like osteopenia and osteoporosis. Inflammation also diminishes bone mineral mass, promoting greater bone deterioration.
Therapies targeting the microbiome, such as dietary modifications and probiotics, are increasingly recognized as potential strategies for preventing and managing osteoporosis. To promote gut and bone health, prioritize a varied, nutrient-rich diet that fosters beneficial bacteria and provides essential components for robust bones. These include foods rich in fiber, collagen, polyphenols, and fermented products. Limit the intake of sugar, alcohol and ultra-processed foods.
In addition to diet, synbiotics, which are combinations of probiotics and prebiotics, can aid in preventing and managing osteoporosis by modulating gut bacteria. These not only support digestion but also regulate immune function, which is intricately connected to bone remodeling.
As we grow older, our brains undergo various changes that lead to cognitive decline. The acetylcholine-dependent neurotransmitter system slows with age, primarily causing older adults to struggle with concentration and working memory. It also contributes significantly to neurodegenerative diseases like Alzheimer's.
Sugar sweetened drinks have faced criticism for years, with diet versions often viewed as safer. A new study ties both sugar-filled and artificially sweetened drinks to elevated chances of metabolic dysfunction-associated steatotic liver disease (MASLD), the severe liver disorder previously named nonalcoholic fatty liver disease. This occurs when fat accumulates in the livers of individuals who rarely or never drink alcohol.
Regular exercise keeps your body and brain sharp as you age. It preserves mobility, supports independence, and may slow cognitive decline. New research shows exercise reprograms the body at the molecular level, fundamentally transforming biological systems from the inside out.